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    Effectively sterilizing surgical instruments is not possible if cleaning is not adequate. Effective disinfection or sterilization of an inadequately cleaned surgical instrument or scope is not possible. Endoscopes should be cleaned with an enzymatic enzyme detergent compatible with the endoscope immediately after use and before manual or automated disinfection. Cleaning involves the entire endoscope, including valves, working channels, connectors and all detachable parts. High level enzymatic enzyme detergent formulations Enzymatic Surgical Instrument Cleaners, in combination with a high level surfactant chemical complex, have been shown to be effective in removing stains, hard water deposits, and encrusted bioburden, while being safe to use for rigid or flexible scopes. Contact us for ONEcleaner Enzyme Surgical Instrument Cleaners, Enzymatic Endoscope Cleaning Sponges, and Enzyme Endoscope Cleaners.

    Customer Service: 1-509-808-3900 email: [email protected]
    Technical Support: 1-509-747-5027 email: [email protected]

    Enzyme surgical instrument cleaners are costly, clinically and financially effective. Manufacturers of surgical instrument usually recommend that Enzyme Cleaning concentrates should be discarded after each use as these products are not microbicidal and will not retard microbial growth. Some manufactures of all-in-one surgical instrument cleaner concentrates include a bacteriostatic agent which will prevent the growth of microorganisms. Some detergent complexes contain antimicrobial-microbicidal substances. Although these agents do not replace disinfection they are designed to reduce the risk of infection to reprocessing personnel by rendering instruments that are clean and safe to handle. The cleaning function efficacy of enzyme surgical instrument cleaners is determined by the ratio of enzymes to bioburden. The higher the proportion of enzymes the higher the efficacy. As a result, if the cleaning solution becomes laden with bioburden from previous cleaning, the efficacy of the enzyme cleaning concentrates is lower. When a cleaning concentrate states that is it "multi-tiered", the inference is that is contains: protease (enzyme) which break protein debris into smaller, more soluble subunits, amylase (enzyme) which catalyses the breakdown of starch, and lipase (enzyme) which breaks up fat-containing debris and carbohydrates. When a detergent cleaning concentrate states that is it "high-level", the inference is that is contains a high concentration of enzymes. When a cleaning concentrate states that is provides enzyme activity the inference is that is contains enzymes but this is usually is a misrepresentation of ingredients for a detergent cleaning concentrate that does not contain enzymes. Enzyme Surgical Instrument Cleaners are effective and they are costly for manufacturers to include in the formulation. As is true for all detergent cleaning concentrates, the most effective test is against your most difficult cleaning challenge. The two most common tests for cleaning concentration efficacy that are commercially available are the "TOSI Test" and the "film test". Be aware that some manufacturers use advertising wordage and product names that imply enzymes are an active ingredient but do not actually include enzymes in their product formulation. Refer to product labels and ingredients for disclosure. Cleaning Surgical Instruments deactivate Prions Creutzfeld-Jakob disease vCJD Optimal Temperature for Cleaning Surgical Instruments and Ultrasonic Cleaner Solution Enzyme Cleaning Concentrates function more effectively at temperatures above room temperature. The optimal range begins as > 22C - 72°F with performance reaching it's peak at 58.3C - 137F. This is often referred to as the optimal temperature for the performance or activity of enzymatic action. The activity of enzymes does not stop at higher temperatures but the level of performance does begin to decrease. Enzyme cleaning concentrates enzyme-detergents and all-in-one cleaning concentrates, which include enzymes, should be used in accordance with the manufacturer's recommendations and the recommendations of the medical devices being cleaned. Pathological prions Creutzfeld-Jakob disease deactivating prions protein and prion contamination approach for cleaning surgical instruments using enzyme surgical instrument cleaners can be the same if the presence of pathological prions including the prions of vCJD Creutzfeld-Jakob disease however the attention to detail is more important. It is known, that prions are unusually resistant to disinfection and sterilization by the physical and chemical methods used for decontamination of infectious pathogens. It is a difficult task to gain a consensus opinion on what constitutes optimal and practical conditions for decontamination of prions. Numerous studies have been conducted, but they do not reflect the reprocessing procedures for surgical instruments in a clinical setting. The clinical setting is critical for iatrogenic transmission, the passing of a disease from an infected individual or group to a previously uninfected individual or group. The method of reprocessing prion contaminated surgical instruments includes (1) decontamination by NaOH or NaOCl for 30 or 60 minutes followed by GL-autoclaving at 121°C for 30 minutes, (2) cleaning and (3) routine PL-sterilizing at 134°C. It is known that some surgical instruments cannot be decontaminated by heat and moisture. Disinfectants have been widely used for this purpose even although the disinfectants are ineffective. The most common practice believes that the only completely safe way to prevent transmission of vCJD is to use single-use surgical instruments. Because of the pervasive distribution of these infectious proteins and the long incubation time of the disease, reprocessing cleaning surgical instruments has been identified as a high risk factor for nosocomial transmission of vCJD. Research has shown that the agent of the vCJD disease, an infectious prion protein, is extremely resistant to today’s sterilization methods; therefore, the argument, “It does not matter if instruments are 100 percent clean, as they will be sterilized,” is definitely no longer valid. Today, we understand that cleaning surgical instruments is as important as the sterilizing the surgical instruments. Today’s surgical instrument cleaning process requires increasingly sophisticated surgical instrument cleaning concentrates. Detergents, which are used in these processes, can be mild, with a neutral pH, or they may be more aggressive, with values in the alkaline range of the pH scale. A number of hospitals and surgical centers are effectively using neutral pH “combination” enzymatic enzyme detergent cleaners for reprocessing surgical instruments. The combination enzyme detergent cleaners provide optimal cleaning as well as the highest possible level of care for surgical instruments and scopes. The manufacturers of surgical instruments strongly recommend the use of Neutral pH cleaners to enhance the passive layer of instrument protection. The use of combination enzyme detergent surgical instrument cleaners has offered the highest level of cleaning outcomes.